Vamps
Deadly Dreamgirls

The local Fishwrap recently ran a poll asking what your favorite locally made film was. As usual, they missed Vamps - Deadly Dreamgirls made in 1995 by Mark Burchett & Michael D. Fox.
The movie is about a guy, Paul Morris, on the eve of his entering the priesthood, running into an old high school friend, Jennifer Huss, who is working in a strip club. Turns out the club is a front for vampire strippers aided by a creepy Charles Cooper and under the domain of Lorissa McComas.

Huss and Morris
Naturally, Morris has to rescue his old crush from the evil vampire sisterhood.
The movie lists locations Trixie's Delight's Cocktail Lounge of Newport, KY, a Little Professor Bookstore in Milford, OH and the Wildwood Inn of Florence, KY.

And of course the Ohio River.

The soundtrack includes tunes by Steve Gatch and The Mortals.
The movie spawned a sequel, Blood Sisters, also featuring Morris & Amber Newman.
It's a shame the Enquirer omitted this masterpiece since they explicitly thank the paper in their credits. That might have had something to do with cleaning up spills, tho.